Leptin Supplements: The Key to Weight Loss?

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Why are many people talking about leptin supplements these days? Today, we’ll share an in-depth review on this topic. Stay tuned!

Leptin is a protein formed in the fatty tissues of the body. It can also be secreted from the liver, placenta, and gastric mucosa.

Once released, it passes into the bloodstream and triggers a signal to the brain. However, when faced with leptin resistance, specific supplements can be of great help.

This hormone is directly associated with satiety control; it plays a vital role in weight regulation.

This is why, in recent years, leptin supplements have become very popular: they are claimed to be able to decrease appetite and facilitate weight loss.

What is leptin, and how does it work?

The hormone was discovered in 1994 and has been studied for its role in regulating weight and obesity in both animals and humans.

Leptin is a hormone produced by fat cells and is primarily related to intake. After eating, it warns the brain that you’re already satisfied and consequently lose your appetite.

Similarly, when you eat abundantly, your levels of leptin in the blood remain elevated for longer.

That is, this hormone communicates to the brain that you have enough stored fat, which reduces your appetite, signals the body to burn calories, and prevents you from overeating.

Conversely, when levels are low, your brain senses hunger increases your appetite, and burns calories at a slower rate. This is the reason why it’s often called the hunger hormone.

Does more leptin means more weight loss?

leptin supplements

Note that people are all different, and therefore, hormonal reactions may vary from one person to another.

For example, in people with obesity, despite having high levels of leptin, their brain does not recognize the signals that the hormone is sending. This is known as leptin resistance.

This means that even if you have more than enough of the hormone available, your brain doesn’t recognize it and thinks you are still hungry.

As a result, you keep eating. Plus, you not only eat more, but it also signals to your brain that you need to save energy, which causes you to burn calories at a slower rate.

In terms of weight loss, more leptin is not necessarily what matters. What really matters is how well your brain interprets the hormone signals.

In other words, due to leptin resistance, more leptin is not proportional to weight loss. Therefore, supplements don’t actually increase leptin levels; they regulate them.

Do leptin supplements work?

Most supplements don’t actually contain the hormone; but rather a mixture of various nutrients to reduce inflammation and increase leptin sensitivity.

Some include alpha-lipoic acid and fish oil, while others contain green tea extract and soluble fiber.

Some research has analyzed the African mango, or Irvingia gabonensis, for its positive effect on leptin sensitivity and weight loss. Ingesting it has been shown to lower leptin levels, which may be conducive to improving sensitivity.

However, more research and studies are needed to conclude whether supplements can influence leptin resistance.

Despite that leptin supplements studies are inconclusive, and more research is needed, some “natural” actions can help improve leptin resistance, increase sensitivity, and promote weight loss without taking a supplement:

  • Increase your physical activity: Research in both animals and humans indicates that regular physical activity can increase sensitivity to leptin
  • Sugary diets can worsen leptin resistance. A study shows that leptin resistance improved in rats on a sugar-free diet
  • Eat more fish: Studies suggest that diets rich in anti-inflammatory foods, such as fish, can lower blood levels of the hormone, improve sensitivity, and promote weight loss
  • High-fiber cereals: A study suggests that eating high-fiber cereals, especially oat fiber, can improve resistance and sensitivity to leptin and aid weight loss
  • Get a good night’s rest: sleep is key to hormonal regulation.
  • Lower triglycerides in the blood: Having high triglycerides hinders the transport of leptin to the brain

Living with the Enemy

Those who don’t know this yet: hormonal imbalances that occur in the body are one of the main causes of weight gain.

Hormonal imbalances are closely related to getting overweight and obese. Sometimes, they can be the cause and other times the consequence.

In other words, when a person becomes considerably overweight, hormonal systems get altered. This is why, in most cases, it’s no longer possible to lose weight with diets and exercise.

For this very reason, some people barely meet their daily food portion and still find it impossible to lose weight.

These hormonal imbalances result in several major problems and illnesses. Highlights include hypothyroidism, Cushing’s syndrome, lack of growth hormone, or Addison’s disease; caused by the lack of cortisol due to damage to the adrenal glands and autoimmune causes.

  • So which are the 4 hormones responsible for all this mess?
  • Why do these hormones cause all these changes within the human body?
  • And more importantly, how can we combat them?

Hormonal imbalances: The Four

leptin supplements

1- Leptin

As we’ve discussed earlier, this hormone was discovered in 1994 by a group of Molecular Genetics scientists at RUNY. Leptin is a hormone produced by adipose tissue that informs the hypothalamus about the size of white fat deposits in the organism.

Many professionals and studies in the field suggest: “that obesity occurs because after a certain amount of leptin, its transport system from the brain to the bloodstream becomes saturated, or because an alteration in its receptors develops at the brain level.”

Hormonal imbalances are linked to being overweight and obese. Sometimes they are a cause and others a consequence. A resistance that causes an exaggerated appetite in most obese people.

Thus creating a vicious circle from which it is challenging to get out.

However, in other cases, leptin has the opposite effect: it reduces appetite and increases energy expenditure. In either case, which foods help us reduce their impact on the body?

A good way to control leptin levels is by eating a lot of fish. Its oil content helps to process food more effectively, in addition to promoting metabolism.

Other ingredients that stimulate this hormone’s potential to lose weight naturally are broccoli, whole grains, almonds, spinach, or carrots.

2- Estrogen

This is a hormone produced by the ovaries and adrenal glands. The main function of estrogen is to determine the sexual characteristics of women.

Such as the appearance of the menstrual cycle or the contour of the hips.

Estrogen levels reach their peak during puberty, then start decreasing until reaching menopause. Throughout this process, estrogens help metabolize fats and distribute them throughout the body.

However, during premenopause, some women secrete more hormones than usual. Causing an increase in toxic fat, fluid retention, or inflammation, among other symptoms.

This estrogen dominance can also increase weight and fat accumulation in the abdominal area, legs, and buttocks.

To avoid these negative effects, the consumption of red fruits, broccoli, Brussels sprouts, cauliflower, radish, asparagus, or whole grains with high fiber content is recommended.

3- Insulin

Insulin is secreted by the pancreas and regulates blood glucose levels. Diets rich in carbohydrates and sugars force the pancreas to generate more insulin to stabilize glucose levels.

When this fails, it accumulates in the form of fat, as explained by medical professionals.

Fortunately, its impact on the body is much easier to control than in other cases. Eating healthy foods and being physically active can help prevent unwanted weight gain.

You may want to read: Insulin Resistance and Weight Loss: Why it Matters

What guidelines should I follow? Calculate calories in the diet. Religiously follow your daily meals and control any stress in the routine; since the latter activates insulin levels and favors cortisol’s secretion, increasing appetite and abdominal fat.

It would be best to base your diet on carbohydrates with a favorable glycemic load, such as whole grains, seasonal vegetables, pulses, and fruits.

These HCs release their sugars into the blood more slowly than refined cereals, in addition to avoiding excessive consumption of stimulating products such as tea, coffee, or sugary drinks.

4- Ghrelin

Like leptin, ghrelin is also known as a hunger hormone. This compound is synthesized in the stomach and takes orexigenic, a substance capable of arousing appetite. Unfortunately, this is not its only effect.

Ghrelin hormone also favors the accumulation of lipids in visceral fat.

The one that is located in the abdominal area and is considered the most harmful; <<according to the results of a research carried out by the Metabolic Research Laboratory of the University of California.>>

As with insulin, it is essential to follow a strict healthy diet to neutralize ghrelin. In addition to not letting more than four hours pass without eating.

Other factors to consider are: avoiding fasting, exercising regularly, and not resorting to strict low-calorie diets. The reduction in caloric intake directly affects the increase in ghrelin and, therefore, the desire to continue eating.

Within this hormone group, fruits, vegetables, legumes, and grains such as oats, sesame, or chia seeds are of great help.

This is because they are rich in soluble fibers that control appetite and the production of this hormone. Speaking of healthy fibers, I also like flax seeds.

Final thoughts and suggestions

There are reasons why weight loss supplements and programs may not work for some people. The truth is quite shocking. In most cases, it’s not the product’s fault.

I’ve found that most people don’t really know the root cause of their problem. Like I said earlier, each individual is different.

You must know what your problem is and then choose a product accordingly.

So, which is a good leptin supplement? If any

leptin supplements: which one is good?

Based on “ingredient” analysis and customer reviews, I’d say there are only two good products on the market. Leptitox and Resurge.

For many years, they’ve genuinely and legitimately been serving the purpose of making your leptin/ghrelin hormones work right and efficiently.

Although they provide the same results, Resurge has added “melatonin” to their formula if your hormonal problems are deeper and cause you lack of sleep.

This means that there’s a good chance your weight problem is not because of leptin resistance only but more of a greater hormonal imbalance.

But how would I be able to tell the differences between a simple leptin resistance issue vs. a more complex hormonal imbalance?

Although leptin resistance and hormonal imbalances share the same symptoms, the latter causes additional discomforts: Dry skin, puffy face, constipation, and most important, lack of sleep. These are telltale signs of hormonal imbalances.

Sleep disorders interfere with your overall metabolism and affect your fat burning mechanisms.

But again, for either one of these disorders, the best two products on the market today are the following:

  1. Leptitox: (website) Perhaps, the pioneers and the first ones to be around. They crafted a natural blend that is good for regulating leptin resistance and detox key organs in your body.
  2. Resurge: (website) As I’ve said earlier, if your problem is due to more generic hormonal imbalances, you may want to check this out. Among its natural ingredients, they’ve added melatonin to improve your sleep, an important factor for your metabolism to function properly.

Nevertheless, both of these products are very similar and get the job done. However, if you have trouble sleeping, you may benefit more from taking Resurge.

I can’t stress this enough: sleep is fundamental for proper metabolism functioning.

Again, my personal claims for both of these products are based not only on customer reviews but, more importantly, on “ingredient analysis.”

Please, don’t hesitate to share your comments or experiences with us. Stay safe and healthy!

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Joel Zazueta

Hey! Joel here; A graduate of Herbalism & Naturopathy Medicine School. My team and I are passionate about finding ways to improve our lives on a daily basis and truly believe in natural alternatives of doing so before seeking traditional medications. However, always consult with your Doctor/Physician first before taking any actions in regards to your health. Stay Safe and Healthy!

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